I've long been fascinated by asynchronous logic design (filed under "magic they don't teach you in school").
And a startup called Fulcrum was one of the more successful at commercializing designs based on these tecniques.
Recently, Intel acquired Fulcrum.
Here, Ron Wilson shares some insights into what applications the asynchronous style excels at, and how to compose the solution play into its strengths:
What is Fulcrum's real leverage?.